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Liverpool hosts first keyhole surgery kidney transplant in Europe
October 9, 2014
A patient at the Royal Liverpool Hospital has become the first person in Europe to receive a kidney using keyhole surgery.
Brian Blanchfield, 51, was given his sister’s kidney in a procedure carried out by a surgeon who flew in from India for a workshop on specialist techniques.
It is common for kidneys to be removed from a donor using laparoscopic or keyhole surgery, but there is only one surgeon in the world, Professor Pranjal Modi from the Institute of Kidney Diseases and Research Centre in Ahmedabad, who uses the method to give the kidney to its recipient.
This process is normally done by open surgery with an incision around three to four times larger.
Transplant surgeon Sanjay Mehra at the Royal arranged for Professor Modi to spend a week at the hospital, where he carried out the operation three times.
Mr Mehra said: “I met Professor Modi at a conference in Vancouver, Canada in 2010. He told me about laparoscopic transplant which was unbelievable at that time. I’d never heard of it. He later invited me to his unit so I learned more.“Professor Modi has more experience than anyone else in the world of doing this procedure so we are very fortunate to have him in Liverpool to share his techniques with the surgical community.
“The keyhole technique has certain advantages, including a much smaller scar. We will now monitor the long-term outcomes for the patients.”
To minimise scarring, the incision was made over a scar Brian has had since his appendix was removed.
Pam was discharged days later and a week after the procedure, Brian was free to go home.......read complete article
Dr. Victor Gura helps mock patient John Kundzins try on a demo version of the Wearable Artificial Kidney on Sept. 5, 2014.
Medical researchers have received approval to begin safety and performance testing of the Wearable Artificial Kidney. The federal Food and Drug Administration and the University of Washington Institutional Review Board accepted the protocol for the clinical trial. Expected to start this autumn in Seattle, it will be the first human study in the United States to be conducted on the device.
The Wearable Artificial Kidney, also known as the WAK, is a miniaturized dialysis machine that can be worn on the body. The carrier resembles a tool belt; the device connects to a patient via a catheter. Like conventional dialysis machines, it is designed to filter the blood of people whose kidneys have stopped working. Unlike current portable or stationary dialysis machines, it can run continuously on batteries and is not plugged into an electrical outlet or attached to a water pipe. The present version weighs about 10 pounds, but future modifications could make it lighter and more streamlined.
Dr. Victor Gura of the University of California, Los Angeles, said, "My team invented the device to untether patients from large dialysis machines." His group wants to give patients with end-stage renal failure the mobility and freedom for such routine activities as walking or shopping while their dialysis runs.....read more
Doctor Performs First U.S. Robotic Kidney Transplants Using a Revolutionary Cooling Technique
Doctor Performs First U.S. Robotic Kidney Transplants Using a Revolutionary Cooling Technique
June 6, 2014
Dr.Mahendra Bhandari, CEO of the Vattikuti Foundation announced that the ongoing Foundation-funded robotic kidney transplant project has had the three first robotic kidney transplants successfully completed in Detroit.
Robotic Kidney Transplantation with Regional Hypothermia was the first medical study in the world to use a novel method of cooling a donated kidney before it is placed in the patient. The surrounding tissue and kidney are also cooled inside the body with more ice while it is being surgically grafted to the recipient.
Dr. Mani Menon, Chair of the Vattikuti Urology Institute at Henry Ford Hospital in Detroit devised the method, which has undergone years of planning and development. The results were recently published in the journal European Urology and presented at the American Urology Association conference in Orlando, Florida last month.
Surgeons from The Vattikuti Urology Institute (VUI) at Henry Ford Hospital (HFH) and from Medanta Hospital in India collaborated at HFH in Detroit to perform robotic kidney transplants May 13th, 14th and 27th at Henry Ford Hospital.
The kidneys, taken from living donors related to the patients, were immediately cooled with sterile ice slush in special gauze jackets and also kept cool inside the body during the transplant procedure. Additional ice slush was delivered by special syringes through a device called a Gelport. The ice slush helps preserve the donated kidney’s tissue while the vein, artery and ureter are connected surgically with the aid of the surgeon-controlled da Vinci robot.....read more
NEPHRON+ project is developing wearable artificial kidney device with remote monitoring
April 15, 2014
End stage kidney disease is a global public health problem with an estimated 2.4 million patients on dialysis. The number of new cases is rising (7-8% annually) due to population ageing and increased diabetes prevalence. The NEPHRON+ project is improving the lives of patients by developing a wearable artificial kidney device, enabled with information and communication technologies for remote monitoring.
An EU-funded research consortium has been developing a wearable artificial kidney that would make it possible for dialysis patients to lead a more full and active life while adding another 10 to 16 years to their life expectancy.
The NEPHRON+ WAKD (Wearable Artificial Kidney Device) is currently undergoing animal trials and will have to pass several rounds of stringent tests in humans before it is ready to be used by all patients with kidney disease. However, the project has reached a stage where commercial partners are ready to take the technology to the next stage. With kidney failure rates on the rise and pressure on hospitals to find more cost effective and clinically effective treatments, the market for wearable dialysis devices could be worth as much as a €15 billion per year, according to Dr Leonidas Lymberopoulos, project coordinator.....read complete article
Henry Ford Hospital cited: World's first surgical innovators for patient safety standards
April 7, 2014
An innovative kidney transplant technique developed by Henry Ford Hospital is credited as the first in the world to use a new set of patient safety standards coordinated by the University of Oxford in England.
The standards are being assembled and offered as a framework for developing, performing and reporting surgical innovations that, unlike new medical treatments, are not under strict regulations and control.
One historic example cited by the Oxford group was the introduction of tracheostomy as a surgical method of treating an obstruction in the trachea. The technique was clearly an innovation at the time, but was not required to go through a randomized controlled trial or other strictures required of new prescription drugs and medical procedures.
Patient safety during the learning curve posed by all surgical innovation has been a matter of concern among surgeons and related professionals for about a decade.
The Oxford group, an international collaboration of such professionals, responded with the creation of IDEAL – its recommended guidelines for Innovation, Development, Exploration, Assessment and Long-term Study.
Three years ago, Henry Ford surgeons and researchers set out to test a minimally-invasive kidney transplant cooling technique conceived by Mani Menon, M.D., chairman of Henry Ford's urology department and a pioneer in robot-assisted surgery.....read more
Trials of wearable kidneys bring hope for dialysis patients
March 6, 2014
WEARABLE artificial kidneys could be available within five years to Australians languishing on dialysis.
One of three promising devices has received approval for human trials.
The device aims to give people suffering kidney failure the chance to reduce their dependence on being plugged into a dialysis machine for hours. The battery-powered device is designed to be worn as a belt and mimics a dialysis machine.
Dr Andrew Davenport, from the Royal Free Hospital in London, said the device could improve a patient’s quality of life. People on dialysis are forced to follow a restrictive diet and could consume only limited fluid.
There are also high rates of depression among these patients.In Australia, most patients have to endure dialysis for 3½ years before an organ donation becomes available.
In Australia, most patients have to endure dialysis for 3½ years before an organ donation becomes available.
Kidney Health Australia medical director Associate Professor Tim Mathew said almost 12,000 Australians relied on dialysis and it's increasing 3 - 4 per cent each year......read more
A new generation of dialysis devices
March 3, 2014
Kidney dialysis is a heavy treatment to undergo and has many side effects. Scientist Prof Dimitrios Stamatialis is starting a new research project into the development of new dialysis membranes for longer and better blood detoxification. The project belongs to The Life Science and Health (LSH) Impuls program and is performed in collaboration between industry, the Dutch Kidney Foundation, Maastricht University and the Maastricht University Medical Center (UMC+). Prof Stamatialis is affiliated with the MIRA research institute of the University of Twente.
Hemodialysis is by far the most common form of dialysis undergone by kidney patients who are dependent on it. This involves purifying the blood outside of the patient's body using an artificial kidney. The artificial kidney is housed in a large dialysis machine. Treatment usually takes place two or three times a week and each session lasts around three to five hours. While dialysis is a lifesaving treatment, it has a significant effect on the kidney patient's body and life. Since the treatment is not continuous, waste products accumulate between dialysis sessions and the patient's fluid balance fluctuates significantly. This means that kidney patients feel exhausted more quickly and are often nauseous. Headaches and itching are also common complaints.....read more
New York: In a major breakthrough, surgeons at India-based Medanta Hospital and Michigan-based Henry Ford Hospital have successfully transplanted kidneys into 50 recipients using an innovative robot-assisted procedure.
In this surgery, called 'Icy' technique, the organ is cooled with sterile ice during the operation. The research advances minimally invasive robotic surgery as a safe alternative to traditional open surgery.
"Minimally invasive surgery reduces post-operative pain and minimises complications in comparison to conventional surgery," said Mani Menon, chair of Henry Ford's Vattikuti Urology Institute.
The researchers knew that kidney function was partially impaired in recipients if blood flow was interrupted for longer than 30 minutes during transplant. So they decided to chill both the donor kidney and the transplant site with sterile ice slush in hopes of increasing the amount of time in which they could safely learn and perfect the robot-assisted surgery, said the study published in the journal of the European Association of Urology.
"To our knowledge, ours is the first study to use renal cooling during robotic kidney transplant. It had already proved useful during minimally invasive prostate surgeries," added Menon.
After three years of planning and simulated surgeries at Henry Ford, 50 patients underwent robotic kidney transplant at Medanta Hospital between January and October 2013......read more
IKDRC performs 400 kidney transplants in 2013
January 3, 2014
AHMEDABAD: Institute of Kidney Diseases and Research Center (IKDRC) staked claim to a record by performing the highest number of kidney transplants in the country in 2013. It claims to have performed 400 transplantations in the year under one roof.
Dr H L Trivedi, head of nephrology at IKDRC said, "We have carried out 308 open surgeries, 51 robotic, and 41 laparoscopic surgeries. Over the years, awareness in patients and relatives has played a major role in building a belief in crossover transplants." The institute has treated 56 crossover transplants and performed 45 transplants with cadaver donor organs.
Trivedi claimed to have made a breakthrough procedure by taking the Mesenchymal stem cells from the abdominal fat of the donor, which are then induced to become regulatory T cells. The process of induction aids in the process and then are infused in the system of the recipient. Due to this procedure, the infused cells resist and fight back the rejection T cells.......read more
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